BISC 101 Lecture Notes - Lecture 4: Endergonic Reaction, Allosteric Regulation, Hydrolysis

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Metabolism transforms mater and energy, subject to the law of thermodynamics via metabolic pathways. Free energy change (g) tell us which reacions run spontaneously. Catabolic pathway breaking down of molecules (release energy) Anabolic pathway creaion of molecule (requires energy) Chemical energy is stored in posiion of electrons. Electrons have highest potenial energy farther away from nucleus. Electrons fall down from high to low e- shells = release of energy. Atoms become more stable (held more ightly) = lower potenial energy = releases energy = spontaneous reacion. Higher entropy = spontaneous (less order/efort to maintain) Exothermic/endothermic is only relaing to heat, whereas exergonic/endergonic is referring to free energy (more general) Exergonic reacions may release heat but also atp for cellular work. Atp = adenosine triphosphate (adenine, ribose sugar, three phosphates) Atp has lots of potenial energy because of 4 negaive charges between the phosphate groups repelling each other. Hydrolysis of atp releases energy and creates adp and p-

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