BPK 305 Lecture Notes - Lecture 1: Colony-Stimulating Factor, Hematocrit, Thrombopoietin

• School: Simon Fraser University
• Department: Biomedical Physio & Kines
• Course: BPK 305
• Professor: Damon Poburko

Document Summary

Serum or plasma (cell free part of blood) =~60% Red blood cells or erythrocytes (the hematocrit) =~40% White blood cells or leukocytes = <5% Platelets or thrombocytes = <1: to determine hematocrit -> blood is centrifuged and the heaviest parts fall to the bottom, ex. hematocrit = 50%, so then rbc = 50% of height. If above ~7-10mm then diabetic: lipids, cholesterol, vitamins, free fatty acids, waste, urea, creatine, uric acid, bilirubin, gases, co2, o2, n2. Cellular constituents: red blood cells -> 5million/ul (largest portion, white blood cells -> 7,000/ul, leukocytes (leuko = white in latin, platelets ->250,000/ul, smaller, total = ~40-45% blood volume. Main role is o2 transport: requires haemoglobin (hb) which is produced with iron, b12, and folic acid, hb has 4 globin subunits, each subunit has a heme group which contains the iron (fe) to bind to oxygen.