HSCI 304 Lecture Notes - Lecture 4: Mathieu Orfila, Forensic Toxicology, Clinical Toxicology

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Iclicker: the occurrence of new disease or mortality within a defined period of observation in a specified population is: The study of the adverse effects of chemicals on living organisms. All substances are poisons the right dose differentiates a poison from a remedy paracelsus: works together with epidemiology to identify causes of disease. Poisons used for suicide, executions and murders in ancient greece & rome. 17th century: increased awareness of toxic effects of exposure to industrial metals and chemicals in common use. Target organ specificity of chemicals: mathieu orfila: description of poisons and their bodily effects. Clinical toxicology: clinical manifestations of disease related to toxic substances. Environmental toxicology: impacts of pollutants upon the structure and function of ecological systems. Reproductive toxicology: environmental chemicals and adverse effects upon the reproductive system. Exposure: proximity and/or contact with a source of a disease agent in such a manner that effective transmission of the agent or harmful effects of the agent may occur.

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