PSYC 2200H Lecture Notes - Lecture 4: Dyskinesia, Brainstem, Serotonergic

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Neurotransmission in four steps the neurotransmitter has to be made and synthesized before is can be released. Two general ways: axon terminal, building blocks from food are pumped into cell via transporters, cell body, according to instructions contained in the dna, transported on microtubules to axon terminal. Initiate other chemical reactions that modulates either the excitatory or inhibitory effect: the amount of neurotransmitter released is called quanta, there has to be enough synaptic vesicles opening up to create an potential. Note: they cannot be left in synaptic cleft. Epinephrine they are involved in positive emotions: amine: serotonin (5-ht) not enough leads to depression, amino acids: glutamate (glu), gamma-aminobutyric acid (gaba), glycine (gly), Note: all act and perform differently, but are all neurotranmitters and follow the same path. Nigrostriatal pathways (orange projections: active in maintaining normal motor behaviour (coordination) Loss of da related to (cid:373)uscle rigidity a(cid:374)d dyski(cid:374)esia i(cid:374) parki(cid:374)so(cid:374)"s disease.

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