BIOL107 Lecture Notes - Lecture 3: Phosphorylation, Endocytosis, Vacuole

• School: University of Alberta
• Department: Biology (Biological Sciences)
• Course: BIOL107
• Professor: Frank Nargang

Document Summary

Selective permeability different concentration of molecules on either side of membrane. Made of phospholipids, membrane spontaneously forms in aqueous environment (phosphates out, lipids in) Aside: oxygen of water is electronegative, polar molecule. H-bonds with other water molecules, stabilizes at low temperature to form ice. Non- polar molecules interact well with each other. Phospholipids are amphiphilic/amphipathic; distinct hydrophilic and hydrophobic region. Form: a) micelle (hydrophobic tails in, hydrophilic heads out): bilayer sheet (single layer, 2 molecules thick, hydrophobic tails in middle, hydrophilic heads out, liposome/spherical bilayer biological membranes. A ring with water inside and outside (hydrophobic tails in, hydrophilic heads out) Proteins intrinsic/integral if embedded in bilayer, extrinsic/peripheral if attached to surface. Carbohydrates glycoproteins/glycolipids, functions: blood type, transplant rejection and immunity, distribution of cells to developing embryo. Cholestrol increases permeability at low temperature (doesn"t freeze), decreases at high temperature (bulky/large) Fluid because proteins float. if two cells fuse proteins will mix in the hybrid cell.