MMI133 Lecture Notes - Lecture 13: Streptococcus Pneumoniae, Fc Receptor, Candida Albicans
2 Feb 2017
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Pathogen: a microorganism that can cause a disease process: primary pathogens: Always cause disease even in healthy immune-competent individuals. Ie: bacillus anthracis: opportunistic pathogen: a microorganism that may cause disease if, pathogenicity: ability to cause disease by evading or overcoming the host defenses given the right circumstances. Ie: candida albicans immunosuppression produced capsule a virulence factor: pathogens with a preferred (cid:498)portal of entry(cid:499) Tropism and preferred portals of entry: virulence: the extent to which the microorganism is pathogenic. Ie: streptococcus pneumonia is a pathogen but only when. Ie: chlamydia trachomatis and mucous membranes, salmonella and the gi system: pathogens with a preferred type of cell to infect (=tropism) Ie: influenza virus and respiratory epithelium with sialic acid residues; uropathogenic e. coli and urinary tract epithelium with d-mannose residues. Age, etc plays into this response then perhaps the infection will not establish)
