MMI133 Lecture Notes - Lecture 22: Staphylococcus Epidermidis, Human Microbiota, Blepharitis
Document Summary
Skin - poor microbial growth environment ( dry, salt, sebum, lysosome, antimicrobial peptides ) Washing reduces numbers but does not eliminate normal flora (re-establishes from hair follicles and sweat glands) high moisture areas have larger microbial populations. Aerobic, but sometimes anaerobic in the hair follicles. Acidic ph, must have low ph tolerable flora. The interior of the eye is sterile fluid. Covered by eyelid, creates warm, moist environment. Thin layer of mucus membrane lining the eyelids and covering the surface of the eye. Bacterial infection contains pus, while the viral infection does not. Inclusion conjunctivitis - chlamydia in the eye (not trachoma) Stye - involvement of eyelid glands and follicles: trachomatis - ocular, genital ( chlamydia becomes inclusion conjunctivitis in the eye ) Ophthalmia neonatorum - gonorrhea within the newborn"s eye. Gram + cocci in clusters (non-motile, spore forming, may or may not include a capsule) 3 important species: s. aureus (primary pathogen)