BIOL 331 Lecture Notes - Lecture 9: Electrochemical Gradient, Membrane Potential, Cell Membrane

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rosefrog223

3 Feb 2018

School

University of Calgary

Department

Biology

Course

BIOL 331

Professor

Vanina Zaremberg

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Document Summary

The difference in electric charge across the plasma membrane is referred to as the membrane potential (voltage gradient) The asymmetric distribution of ions across the plasma membrane produces both: a chemical (concentration) gradient, and an electrical (voltage) gradient, both of which contribute to the formation of the electrochemical gradient. When the concentration gradient and membrane potential balance each other, the electrochemical gradient for the ion is zero, and there is no net flow of the ions through the channel. It is important to realize that although there is no net flow, there is still motion of ions across the membrane, just that there is an equal concentration of positives and negatives on either side of the membrane. The membrane potential at which equilibrium is reached is called the equilibrium potential for the ion. Important: the value of the membrane potential can change depending on the cell type.

Related Questions

During active transport in the neuron, the outside of the cell is _________________ and the inside is _______________.

positive, negative

more positive, less positive

more negative, less negative

negative, positive

In active transport, _____________ provides the energy to move molecules against their concentration gradient.

nucleus

potassium

sodium

adenosine triphosphate

________________ proteins can change shape when moving substances across the membrane.

Proteins that can be open or closed, based on different conditions, are called ___________.

bypass proteins

channel proteins

selective proteins

gated

Tunnels that allow charged ions to move easily across the plasma membrane without the use of energy are called ____________________.

channel proteins

glycolypipd proteins

phospholipid proteins

carbohydrate chains

____________ and ____________ make it easier for molecules to move across the plasma membrane.

small, negatively charged

small, positively charged

small, no charge

large, negatively charged

large, positively charged

Cellular biology answer check. please check if my answers arecorrect or not.

1) The concentration of ions inside a cell is the same as theirconcentration outside of the cell. True or false? (i chose falsesince having equilibrium inside a cell is bad)

2) Membrane transport proteins...

a)...transport membrane potentials between cells

b)	...transport membranes from the ER to the Golgi

c)	...are made up of phospholipids

d)	...transport molecules across membranes

i chose d

3)The electrochemical gradienttakes into account:

a)	The concentration of solutes on either side of themembrane.

b)	The overall charge on either side of the membrane.

c)	Both of these.

i chose C. (although i am sure that overall charge matters, Iwasn't sure if concentration of solutes are taken account.)

4) If no energywere expended by an animal cell:

a)	Both gradients would be depleted

b)The K+ gradient would maintain itself.

c)	None of these

d)	The Na+ gradient would maintain itself.

I chose d) mainly because I think Na+ gradient exist in animalcell and not K+ gradient.

5) Which of the following is a true statement aboutactin?

a)	Once actin has polymerized, it never depolymerizes.

b)	Actin is a transmembrane protein.

c)	Actin can form branched networks.

d)	Actin filaments are organized into hollow tubes.

I chose c. can't explain why.

6)Ion channels:

a)	Form a hydrophobic channel through the membrane

b)	Have filters that let sugars through

c)	Are selective for particular ions (only the

taupeshark376

1. The plasma membrane of liver cells contains a glucose uniportthat transports glucose by facilitated diffusion. When the[glucose] is higher inside the liver cell than the [glucose]outside the liver cell, the glucose uniport will

A. couple the transport of glucose out of the cell to thehydrolysis of ATP

B. couple the transport of glucose into the cell to thehydrolysis of ATP

C. switch to a closed conformation, allowing no transport ofglucose

D. transport glucose out of the cell by passive transport

E. transport glucose in of the cell by passive transport

2. Unlike the positive charged ion shown in the middle diagramof figure 11-4B, K+ is higher in concentration inside the cell. Howwill the membrane potential of a cell at rest (shown in both themiddle and right-hand diagrams of Figure 11-4B) affect theelectrochemical gradient for K+?

A. The membrane potential will increase the electrochemicalgradient

B. The membrane potential will decrease the electrochemicalgradient

C. The membrane potential will have no effect on theelectrochemical gradient

3. Which of the following proteins carries out activetransport?

A. gluclose symport

B. Bacteriorhodopsin

C. ABC transporter

D. NA K pump

E. All of the above

4. Aquaporin will not transport Na+ ions because

A. Two asparagine residues in the channel prevent the passage ofNa+ ions by binding the oxygen of each water molecule as it passesby

B. Na+ ions are repelled by the positive charges at the entranceto the channel

C. Na+ ions cannot make contact with the carbonyl (C=O) groupson all four sides of the channel

D. The passage of Na+ ions is energetically unfavorable becauseone side of the channel is hydrophobic in nature

5. The acetylcholine receptor is different from other channelproteins we have discussed, such as the K+ leak channel,because

A. The acetylcholine channel is composed of a single polypeptiderather than multiple subunits

B. The acetylcholine channel transports Na+ ions against theconcentration gradient for sodium

C. The acetylcholine channel has a much smaller diameter thanother channel proteins

D. The acetylcholine channel transports ions with theirassociated shell of water molecules

E. The acetylcholine channel is always open, and never switchesto a closed conformation

6. After opening briefly along the axon of a neuron,voltage-gated ion channels switch to an inactivated conformationthat slowly returns to the original closed conformation of theprotein. This slow change in conformation, requiring about amillisecond, is important because

A. all of the ions that were transported across the membranewhen the ion channels were open must be actively transported backto the other side of the membrane, restoring the originalconcentration gradient, before the ion channels can open again

B. ATP hydrolysis is necessary to drive this energeticallyunfavorable change in conformation

C. it prevents the action potential from reversing direction andtraveling back toward the cell body of the neuron

D. the channel protein must be dephosphorylated in order tocomplete the transport process and return to the originalnonphosphorylated conformation

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BIOL 331 Lecture Notes - Lecture 9: Electrochemical Gradient, Membrane Potential, Cell Membrane

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