BIOL 331 Lecture Notes - Lecture 24: Rectangular Function, Zipper, Desmosome

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Cells can contact each other through specialized contacts. The proteins in these contacts interact specifically to others on the neighbouring cell or substratum, and other proteins inside the cell. The properties of these proteins and their interactions dictates their function. Found at the top of the cell. Tight junctions form close contacts between cells. Regulate the passage of solutes between cells. Not completely blocked, there is control as to how much the (cid:1684)zipper(cid:1685) should open to allow the flow of ions and other solutes. Blocks diffusion of integral membrane proteins between the apical and basolateral membranes of the cell. Restricts plasma membrane proteins to a particular domain of the membrane. Proteins from the cells involved are secreted and interlock, allowing cell communication. Connect the external environment to the actin cytoskeleton. Form a belt that encircles the cells near the apical (top) surface. Interact with multiple proteins to form a (cid:1684)cytoplasmic plaque(cid:1685) on the inner surface.

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