BIOC 2580 Lecture Notes - Lecture 25: Mitosis, Heredity, Base Pair
22 Mar 2017
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Rna is rapidly hydrolyzed under alkaline conditions; dna is much more stable the 2" hydroxyl of rna, which is absent from dna, acts as a nucleophile in an intramolecular displacement, breaking the phosphodiester linkage. //end of second half i (weeks 7-8)" notes secondary structure of dna. Erwin chargaff and his colleagues (late 1940s) found that in all cellular. Dnas the number of adenosine residues were equal to the number of thymidine residues, and the number of guanosine residues were equal to the number of cytidine residues this is known as the chargaff"s rules". A = t, g = c however, the % of gc and at are varied among different organisms. With advancement of dna technology, scientists are able to synthesize small oligonucleotides of a defined sequence these smaller dna molecules from well-ordered crystals and give. Spot" diffraction patterns such as those that can be obtained with protein crystals.
