EQN 3050 Lecture Notes - Lecture 4: Hyperthermia, Myocyte, Water–Electrolyte Imbalance

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Liver glycogen meets glucose needs of the organism as a whole. Muscle glycogen meets glucose needs of muscle in which it is stored. When broken down, glycogen yields glucose-6-phosphate which can be shunted into glycolysis to . - fuel muscles and the brain, fuel for other cells via the liver, or production of nadph. Higher pre-exercise results in higher utilization of glycogen during exercise. Glycogen binds to glycogen phosphorylase, increasing its activity. Muscle glucose uptake appears to be lower with higher pre-exercise glycogen levels. Low glycogen following exhaustive exercise increases insulin sensitivity and glu uptake by cells in humans but. ~ doesn(cid:495)t seem to happen in horses, the relationship btw equine muscle and insulin is very complex. ~ direct relationship in humans but not in equine muscle ( have a lot less info here) Glycogen re-synthesis is almost to pre-exercise levels 24hr after cessation of exercise.

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