EQN 3050 Lecture Notes - Lecture 13: Globulin, Carbonic Anhydrase, Sodium Bicarbonate

• School: University of Guelph
• Department: Equine
• Course: EQN 3050
• Professor: Wendy Pearson

Document Summary

Respiratory and metabolic processes control their balance: co2 combines with water to form carbonic acid (hco3) dissociates to generate h+ and hco3- This is the bicarbonate-carbonic acid system: acid-base balance is represented by the relationships among pco2, ph and the hco3- in blood plasma. What influences formation of h+: exercise. Acid-base responses to exercise moderate/high intensity exercise. H2o + co2 h+ + hco3- water + carbon dioxide hydrogen + bicarbonate increased co2 = decreased blood ph = respiratory acidosis. (cid:449)he(cid:374) the lu(cid:374)gs (cid:272)a(cid:374)"t re(cid:373)o(cid:448)e e(cid:374)ough of the co2 produ(cid:272)ed (cid:271)y the (cid:271)ody decreased co2 = increased blood ph = respiratory alkalosis. Increased respiration increases blood ph beyond the normal range. How does hco3- buffer blood? chloride shift occurs when hemoglobin receives co2 and gives up o2. The major contributor to presence of extracellular hco3- [h+] = k * [co2]/[hco3-] ph = pk + log [hco3-]/[co2] in terms of pco2 ph = 6. 1 + log [hco3-] / 0. 0301 pco2.