MBG 1000 Lecture Notes - Lecture 6: Male Reproductive System, Zygosity, Y Chromosome
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6 Apr 2016
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Monday, february 22, 2016 and wednesday, february 24, 2016 sex linkage. Humans: 2n=46: 22 pairs of autosomes and 1 pair of sex chromosomes. Hemizygocity: when one copy of a gene is present instead of the customary two: there is no counter allele, gene deleted, hemizygous chromosome. When only one copy is present in a diploid organism. Sex-determining region y (sry) gene: encodes the tesis determining factor (tdf) Only found in males: passed from father to son only, found in all male descendants of afected male. Concepts of dominant or recessive does not apply: only one allele (on y) ever present in any one male, y-linked genes are hemizygous. Examples of y-linked disorders: male inferiliiy (1:2000 1:3000 in us, defects in development of male reproducive system. Female-speciic traits and many others: larger coding capacity than y chromosome, all genes on x chromosome deemed x-linked . Paterns of inheritance: male ofspring: x chromosome from mother.
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Females inherit X-linked traits from their maternal parent only. | ||
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