MBG 2040 Lecture 3: Lecture 3 - Linkage

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Linkage and mapping: independent assortment can mean that we have 2 genes on different chromosomes. All somatic cells would be genetically identical. The little equal signs signify that genes a and b are on different genes. Can do a dihybrid test cross to figure out the offspring produced: some genes are said to be closely linked and crossing over of genes to the homologue occurs during prophase i of meiosis. The frequency of crossing over between genes a and b is a measure of the distance between genes a and b. Independent assortment can imply that the genes are on two different chromosomes or are 50 or more map units apart from each other. Trans (one recessive one dominant gene on the chromosome) The genotype of the parental gametes indicates the formation of the alleles on the dihybrid parent i. e. dihybrid x test cross. Therefore, the dihybrid: determine the map distance.

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