POPM 3240 Lecture Notes - Lecture 8: Chronotype, Immunosuppression, Cortisol

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Device or process designed to detect or quantify a sign, substance or response in an individual or group. Sick vs healthy, affected vs not affected, mild vs severe vs moderate, affected vs don"t know vs not affected. The apparently healthy individuals, not because they are suspected. Early detection of a pathological process or impaired productivity. Confirm, classify, guide treatment or aid in prognosis of clinical disease. No misdiagnoses, all correct identification of disease. Able to determine whether a disease is truly present. Tests that are not gold standard can cause problems. Will the test identify disease given the individual is diseased (and vice versa) Provide useful info to investigate or diagnose process. Given test positive, the probability of real diseased. E. g. smallpox and cowpox virus are so similar that their antibodies can react to both. Previous vaccination and exposure if measuring antibodies. Now creating antibodies with signals if they are from vaccination.

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