BIOL 2410 Lecture Notes - Lecture 35: Paracrine Signalling, Ovulation, Egg Cell
Document Summary
Gnrh -> stimulates secretion of lh and fsh. Fsh works on seratoli cells of the testes. Fsh secretion is also controlled activin and inhibin. Paracrine signals needed to direct mitosis and meiosis of sperm cells. Lh works on intestinal cells to stimulate testosterone production. High lh levels inhibit gnrh release -> negative feedback. Primary sex characteristics -> development of internal and external genitalia. Secondary sex characteristics -> depending of the voice, growth of body hair, change in body shape, protein anabolism, libido. Two structures located in the pelvic cavity near the opening of the fallopian tube. An inner medullary layer containing nerves and blood vessels. An outer layer called the ovarian cortex -> houses follicles. At birth females contain ~ 500,000 primary oocytes surrounddd by a single layer of granulosa cells. Most will eventually die -> will not develop. Some primordial follicles mature -> primary oocyte increases in size. Granulosa cells divide -> remain in a single layer.