MBIO 1010 Lecture Notes - Lecture 24: Adaptive Immune System, Immunogen, Hapten

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Tolerance inability to mount an adaptive immune response against self-antigens . Immune system cells that recognize self-antigens are destroyed during development. Primary response - the first time a new pathogen is encountered, the adaptive immune response is weak . The major result is the production of immunologic memory . Secondary response - the next time that pathogen is encountered memory cells are ready to respond : response can be so quick that the pathogen is unable to cause disease, ie. immunity. End of secondary response, you produce memory (always put them back on the shelf). Immunogen any foreign particle that can induce an adaptive immune response o. Normally large molecules proteins, polysaccharides, some lipids . Antigen any substance that can react with antibodies or receptors on adaptive immune system cells. Antibody protein made by the immune system that can bind to, and inactivate foreign antigens .

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