BIOL130 Lecture Notes - Lecture 1: Passive Transport, Photosynthetic Reaction Centre, Cytosol
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30 Oct 2016
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Membrane proteins: a protein associated with a lipid bilayer; can be either integral (transmembrane) or pheriphal. Membrane proteins transport particular nutrients, metabolites and ions lipid bilayer and also perform many other functions as well such as anchor the membrane or act as receptors that detect chemical signals. Proteins that are directly attached to a lipid bilayer are known as integral membrane proteins. Remaining membrane proteins are known as peripheral membrane proteins. All membrane protein have a unique orientation in the lipid bilayer which is essential for their functions. Hydrogen-bonding is maximized if the polypeptide chain forms a regular -helix, and so the great majority of the membrane-spanning segments of polypeptide chains traverse the bilayer as -helices. The proteins that form pores are more complicated, usually possessing a series of - helices that cross the bilayer a number of times. In many of these proteins, one or more of the transmembrane regions are formed from.
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