BIOL130 Lecture Notes - Lecture 9: Spindle Apparatus, Sister Chromatids, Actomyosin Ring

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Division of genetic material that produces daughter cells genetically identical to parents. Accompanies by cytokinesis (division into 2 separate cells) Division of genetical material to produce daughter cells with half of hereditary material found in the parent cell. Involved only in the production of gametes (eggs/sperm) Purpose of cell division: growth & development, asexual reproduction, repair. 2 copies of each essential to survive. Highly variable in number (eukaryotes 10-50) = human 46 (22 autosomal, 1 pair sex), silkworm. Process: dna double helix wrapped around histone proteins, tightly packed dna with histones, chromosome in extended form, condensation of chromosome = prep for mitosis/meiosis, entire mitotic chromosome (folded, more compact) Homologous chromosomes: same arrangement of genes (not combined by centromere) Sister chromatids: replicated gene, attached by centromere (identical) Where cell spends most of its life. G1: parent cell has 2 unreplicated chromosomes, most of cell"s growth. S phase & g2: 2x dna because replication and synthesis occurs.

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