BIOL303 Lecture Notes - Lecture 15: Paraxial Mesoderm, Neural Crest, Lateral Plate Mesoderm
Document Summary
Chordamesoderm: forms the notochord, which will eventually degenerate by apoptosis, some remains in the nucleus pulposus of intervertebral discs. Intermediate mesoderm: forms the urogenital system (kidneys, gonads, and their ducts) and the cortical portion of the adrenal gland. Lateral plate mesoderm: forms the circulatory system (heart, blood vessels, blood cells) as well as the lining of the body cavities and all the mesodermal components of the limbs (except muscle). Somite: segmental block of paraxial mesoderm adjacent to the notochord, arises form the epiblast on either side of the primitive streak, stem cells left behind during the regression of hensen"s node, differentiates to form: Sclertome: becomes vertebral bodies, ribs, and outer dorsal aorta. Anterior to posterior elongation: involves cell proliferation, migration and size expansion, creates the segmental plate that allows for segmentation. Maturation zone: lots of cell proliferation to create more cells. Notochord: cells develop vacuoles that increase cell size and expands the notochord, pulling along the presomitic mesoderm.