BIOL373 Lecture 5: Endocrine
10 Mar 2017
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Document Summary
Experimental endocrinology: remove, replace or change the suspected gland to observe resulting changes, classical hormones are de ned through manipulation experiments. Berthold: removal of chicken testes changed their behaviours, suggesting that there was a neural connection to the testes, but transplantation experiments showed that it was not a neural but that the signals were transported by the blood. Sequard: injected himself with animal testes extract and claimed sexual rejuvenation, results due to placebo not testosterone. Endocrine: glands that secrete into blood vessels, chemical signals produced stay within the body. Exocrine: glands secrete into a lumen and chemicals travel outside the body (ie skin or alimentary canal) Nonclassical hormones: are secreted by a tissue other than a gland, can act locally by diffusing through ecf rather than the blood, can be released by neurons and act as neurotransmitters. Neurohormones: secreted by a neuron into the blood stream, often releasing hormones. Adrenal medulla: chromaf n cells (modi ed sympathetic neurons) secrete epinephrine.
