KIN217 Lecture Notes - Lecture 2: C-Terminus, N-Terminus, Hydrogen Bond

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Linear polymers formed by linking the -carboxyl group of one amino acid to the - amino group of another amino acid. Peptide bond (amide bond) the linkage joining amino acids in the protein. Hydrolysis the loss of a h2o molecule during the formation of a dipeptide from 2 amino acids. Polypeptide chain a series of amino acids joined by peptide bonds. Residue each amino acid unit in the polypeptide. A polypeptide chain has directionality (polarity), because its ends are different: organized starting with amino group (amino terminus) and ending with carboxyl group (carboxyl terminus) Side chain variable part (the r groups in the diagram below) Helix, pleated sheet and turns are formed by hydrogen bonding of the polypeptide backbone (nh and co groups) Polypeptide chains can change direction by making reverse turns and loops. Loops are usually composed of amino acids with hydrophilic r groups slide) Form long fibres that serve a structural role for cells and tissues.

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