BIOL 200 Lecture 22: Post-Golgi Trafficking
Document Summary
Topic 4. 3 golgi & protein processing (continued) The golgi works just like assembling a jet. Different resident proteins are present in different cisternae of the golgi stack. Localization of three different enzymes that can be stained to show up in tem sections. Note: each one is located in a specific compartment of the golgi. Co(cid:374)sider the dile(cid:373)(cid:373)a : must accommodate all possible kinds of cargo (i. e. large and small proteins, resident glycosyl transferases must maintain their relative position in the golgi stack. Pathways beyond the trans golgi network (tgn: signal-mediated diversion to lysosomes. Exocytosis includes the following 2 pathways: constitutive secretory pathway (constitutive secretion, signal-mediated diversion to secretory vesicles (for regulated secretion) Constitutive secretion: happens all the time, no signal required for vesicle release, vesicle formation generally does not require coat proteins, also called the default secretory pathway, destined for plasma membrane.
