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CLST 110 Lecture 1: CLST 110 FULL SEMESTER NOTES

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School
UBC
Department
Classical Studies
Course
CLST 110
Professor
Williams

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Document Summary

Office: buch c330 m/w 2-3 pm, th: 11-12 arden. williams@ubc. ca. Admired the culture, considered this particular period better than the prior or after. Would we still call it a golden age with our different values. Golden age phrase goes back to 18th cent. Herodotus was the father of history, writer of the first prose narrative history in greek on the invasion of mainland greece by the persians. 2100 is approx date when greek speaking people enter greece, a different group that suddenly appear. 30 bc is when the romans conquered the last greek independent colony what we will cover. When people start practicing argiculture, settle villages, build walls and roads, thinks about utilities. Acceleration of prosperity and population, using braze for tools, greek speakers arrive, reaches cataclysmic end and civilization collapses. Disapears from historical record, the people lost technology and labour to build the big stone palace complexes from the bronze age.

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1. a. Consider the following sequences, which are pieces of a larger, independently folding polypeptide. Which sequence is more likely to form an alpha helix, and which is more likely to form a beta-hairpin—a two-stranded antiparallel beta-sheet in which the strands are separated by a turn?

Sequence A: I F I C T T G P N A T V I C V F V

Sequence B: M D R L M E A M A K L D H L L A E

b. How do the structures of the residues I, V, and T versus L and M contribute to the conformational preferences of these two sequences?

c. Which residues likely form the turn between the stands in the beta-hairpin? Why are these residues suited for this structure?