PSYC 101 Lecture Notes - Lecture 5: Inhibitory Postsynaptic Potential, Excitatory Postsynaptic Potential, Resting Potential
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PSYC 101 Full Course Notes
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Week 5 lecture 1: the resting membrane potential. Neurons communicate via neurotransmitter molecules, when a neurotransmitter molecule binds to a postsynaptic receptor, it can have one of two localized effects: 1 depolarize the membrane/ excitatory postsynaptic potential (epsp: eg. Decrease the membrane potential from -70 to -67: increase likelihood that neuron will fire action potential. 2 hyperpolarize the membrane/ inhibitory postsynaptic potential (ipsp: eg. Epsps and ipsps sum spatially and temporally: spatial: the effect of multiple neurons can be combined together, temporally: the same neuron can have a stronger effect if it repeatedly sends the same signal. If they happen in rapid succession can summate to create larger one. Ap generation and conduction are the result of voltage activated ion channels. Impossible to elicit another action potential during refractory period. Tripartite synapse additional astroglia process to wrap synapse to insulate it and binds neurotransmitter.
