BIO 3170 Lecture Notes - Lecture 12: Non-Coding Rna, Ribosomal Rna, Messenger Rna
11 Apr 2018
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Document Summary
Contribute to the structure of the ribosome trna. Carry the amino acids and act as adaptors during the translation process snrna. Involved in maturation and covalent modi cation of rrnas mirna. Involved in telomere synthesis, x chromosome inactivation, transport of proteins to the er. Eukaryotic gene and mrna structure pre-mrna is an exact copy of the coding strand of genomic dna - contains introns mrna: has protein coding information, has been spliced and modi ed. Mrna maturation: occurs in the nucleus: includes: 5" capping, 3" polyadenylation, splicing. Mature mrna will be exported to cytoplasm for translation after quality control check. *5" utr: starts at the rst transcribed nucleotide and ends at the aug initiation codon. *3" utr: starts at the rst nucleotide after the termination codon and ends at the polya sequence. Can contain regulatory elements for mrna stability and/or mrna localization. Increases ef ciency of splicing of the rst exon. Increases ef ciency of mrna export from nucleus.
