BIO 3302 Lecture Notes - Lecture 16: Renal Function, Oncotic Pressure, Renal Corpuscle

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Molecules move from blood of glomerulus into. Bow(cid:373)a(cid:374)"s capsule (filtration step first step of urine formation. From the renal artery, the afferent arteriole brings blood to the glomerulus. Blood that leaves the glomerulus is still oxygenated (or arterial blood) and leaves via the efferent. From there it goes to a second capillary bed; if capillary bed is around the proximal/distal tubules it is (cid:272)alled the (cid:862)peritubular capillaries(cid:863) In mammals/birds, the capillary bed around the loop of he(cid:374)le is (cid:272)alled the (cid:862)vasa recta(cid:863) These capillary beds are important for urine formation and they are a site of oxygen delivery to the tissues and removal of waste products. Blood leaving the peritubular capillary bed is deoxygenated and then goes off to the renal vein. 15-20% of water and solutes are filtered. 125ml/min is filtration rate; the volume of filtrate produced in a day is 180 l. This is not sustainable; so we reabsorb most of it.

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