BIOA01H3 Lecture Notes - Lecture 1: Okazaki Fragments, Indian Rhinoceros, Single-Nucleotide Polymorphism
23 Sep 2016
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A body of a rhinoceros has been found. There is blood on the nearby bushes and the rhinoceros is missing its horn. How could researchers distinguish the dna of african rhinoceros (diceros bicornis) from indian. Rhinoceros (rhinoceros unicornis): see article doi:10. 1038/3405 on blackboard for the answer, dna from poached rhinoceros horn compared to reference samples. Single nucleotide polymorphism (snp) typing and dna nucleotide sequencing. Compare sequences from unknown sample to reference sequences. 2 samples of rhinoceros horn confiscated in frankfurt international. Dna replication: separation and stabalization: helicases, single stranded binding proteins, topoisomerases, synthesis of new dna strands: polymerases, semi-discontinuous dna replication: anti-parallel strands, leading and lagging strands, (telomerases in eukaryotic dna replication) The top is the 5" end and the bottom is the 3" end. Watson and crick (with data from wilkins and franklin) Reading suggestion: the double helix [book][only for interest]
