BIOA01H3 Lecture Notes - Lecture 4: Aminoacyl Trna Synthetase, Start Codon, Transfer Rna

• School: UTSC
• Department: Biological Sciences
• Course: BIOA01H3
• Professor: Aarti Ashok

Document Summary

Shine-dalgaro sequence thus can have multiple proteins coded for it (polycistronic) Initiation in eukaryotes begins at the 5" cap and the universal start codon is aug mrna is translocated until ribosome reaches aug (start codon) 3 nucleotides are read at a time codons. Has (cid:374)u(cid:272)leotide cca at its (cid:1007)" e(cid:374)d, a(cid:374)d (cid:1007)" oh of a is the atta(cid:272)h(cid:373)e(cid:374)t site for the a(cid:373)i(cid:374)o a(cid:272)id. Large subunits has sites for the trna e most codons specify amino acid according. Once complex reaches aug, initiation factors are released and the large ribosomal subunit joins, while trna comp. to next codon enter a site. Elongation is the continuous repeat of these steps. Termination is when stop codon is reached (uaa, Either strand can serve as template, > translation always starts at aug, all mrna contains untranslated region [end] (cid:894)3" utr(cid:895), 5"utr beg. are regions that are untranslated.