BIOA01H3 Lecture Notes - Lecture 10: Twin, Ovulation, Meiosis
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BIOA01H3 Full Course Notes
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Complex traits are influenced by the env. eg. human blood pressure is influenced by fatty, high salt diets. Complex traits are influenced by multiple genes. Eg. corn #2 has interplay between genotype environment that completely changes when put in its optimal environment. No 2 genotypes are best, no environment is best for specific genotype. Galton"s data for height suggests that indi(cid:448)iduals progressi(cid:448)ely populate to(cid:449)ards the mean regression towards the mean. Meiosis: recombination and segregation breaks up combination of genes that result in extreme phenotypes (very tall, short etc. ) Heritability: the proportion of the variation between individuals that can be attributed to genes alone. Fraternal (dizygotic) 2 separate eggs produced by double ovulation fertilized by different sperm. Concordance - when one twin has trait, what are chances other twins also has it. Similar concordance rate for identical/fraternal = less genetic importance. Factors influence specific individual personalized medicine tailors treatment to genetic risk factors and person"s indi(cid:448)idual lifestyle.
