BIOA01H3 Lecture Notes - Lecture 11: Carcinogenesis, Lysogenic Cycle, Nuclear Membrane
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BIOA01H3 Full Course Notes
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Polyhedral: multiple viral protein, capsomeres and multiple faces. +ve sense = if seq. is same as mrna. Ve sense = if seq. is complimentary to mrna. Have 2 cycles: lytic and lysogenic cycle. Whether each process happens is dependent on the environment, abundance of cells etc. Non-enveloped viruses poliovirus (infects nerve cells) Bilayer of nuclear envelope allows for fusion with plasma membrane of target cell. Can result as a response to viral infection. Cancer is a genetic disease oncogenesis results in tumours and can be brought forth by carcinogens, mutations and viruses. V-src: vital gene in rsv that is essential for oncogenesis. Mutant v-src showed that protein to protein interaction was important and that it likely interacted w/ many host cell proteins. Function was different and its expression did not lead to cancer! C-src is a kinase phosphorylates its targets v-src and c-src differ in sequence v-src is a mutant version of c-src that was captured by.