BIOA02H3 Lecture Notes - Lecture 13: August Krogh, Hemoglobin, Torpor
BIOA02 Module 2 Lecture 13: Introduction to
Physiology
Types of Physiology
Medical/Clinical Physiology
-university medical departments
-university biology departments
-rodent experimental models
-clinical trials on humans
Comparative/Animal Physiology
-university biology departments
-university field stations
-invertebrate, fish, amphibian, reptile
-avian, mammalian experimental models
Comparative Physiology
-august krogh principle: for every question in biology there is an ideal model system
1. Mechanistic physiology 2. Evolutionary Physiology 3. Environmental Physiology
General Themes in Physiology
1. Structure – Function Relationships
2. Acclimatization and Adaptation
3. Feedback/Feedforward Control Systems
4. Conformity and Regulation
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BIOA02H3 Full Course Notes
Verified Note
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Document Summary
August krogh principle: for every question in biology there is an ideal model system: mechanistic physiology 2. General themes in physiology: structure function relationships, acclimatization and adaptation, feedback/feedforward control systems, conformity and regulation. Example: the fish gill is optimally designed for gas exchange. It is much more efficient than the mammalian lung. Acclimatization: a physiological change caused by moderate to long exposure to a given environmental condition either naturally or in a laboratory setting. Example: exposure to high altitude and therefore low o2 causes a change in brain mechanisms that regulate breathing. Adaptation: physiological mechanisms that have developed over long periods of time due to constant exposure of a population to a given environmental condition. Example: hemoglobin binds oxygen with a greater affinity in people who are born, raised and live at high altitudes. Feedback: a physiological response to changing conditions to restore homeostasis.
