BIOB34H3 Lecture 7: Lecture Notes _ Week 4

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Equilibrium: state that all physical systems evolve towards in the absence of external energy. Objects always move down energy gradients without external energy. Chemical potential: amount of work done by group of molecules: determined by concentration of molecules, different from potential energy stored in covalent bonds. By laws, as particles randomly move and bump against each other, they spread out evenly. When the chemical potential is different inside the cell as compared to the outside, it means it is not at equilibrium. Most animal fluids are also not in equilibrium with the environment maintained throughout negative feedback. Fish keep the concentration of salts in their bodies very different from the water they live in requires energy, molluscs do not. Molecules with electrical charges move down electrical potential gradients (measured in v: 1v = 1j/c: positively charged particles move down electric potential gradients, negatively charged particles move up them.

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