BIOB51H3 Lecture 10: Tutorial 1 (lecture 10 cont.)
Document Summary
Powerful tool of evolution: e. g. , amopheles gambiae, vector for malaria: where you can insert allele in males that prevents females from making eggs, genetically engineered. We can exterminate this species from earth by using this technology: after many generations, either extinction or natural selection striking back. Slide 40: without mutation, evolution would not be possible since no variation. If beneficial, expect selection for mutant allele; if deleterious, selection for normal allele: normal allele refers to wildtype allele. Slide 43: selection can happen at any point in this life cycle (adult, gamete) If so(cid:373)e i(cid:374)dividuals do(cid:374)"t (cid:373)ate, that"s selectio(cid:374) ((cid:374)ot selected as a (cid:373)ate, could die, (cid:373)alfo(cid:396)(cid:373)atio(cid:374) of gametes: some individuals may lose sperm competition, not all zygotes survive maturity, thus imposing selection. Slide 44: take single cell of e. coli and put it in nutrient limited medium, mutation only source of genetic variation.
