EESA10H3 Lecture Notes - Lecture 10: Risk Assessment, Food Industry, List Of Iarc Group 2B Carcinogens
5 May 2019
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Document Summary
Introduction to risk assessment a regulatory science there is connection. Must sometimes take action without full scientific understanding of hazard. Risk assessment sets default procedures for bridging gaps in scientific understanding. Basic framework: evaluate exposure and toxicity; bring this information together to characterize a health risk . Stages of risk assessment: problem definition, identify contaminant, receptor analysis, pathways analyses, exposure assessment, toxicity assessment, risk characterization, uncertainties, critique. Incremental or total exposure: receptor analysis, organism, species or groups of species exposed to stressor, define scenario: Length of exposure (life time, 20 years latency for cancer) Define routes of exposure (ingestion, inhalation, dermal) Determine rate of exposure from each route. Characterized activity pattern that results in exposure. Sensitive subpopulation (recent interest in children: pathways analyses, determine environmental fate that results in exposure to receptor, evaluate routes of exposure, quantify amount of exposure (dose, methods.
