HLTB15H3 Lecture Notes - Lecture 1: Randomized Controlled Trial, The Lancet, Random Number Table

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Note: these objectives are addressed in week 2 and week 3 tutorials. Readings: aschengrau & seage, chapter 7, galante j, dufour g, vainre m, et al. A mindfulness-based intervention to increase resilience to stress in university students (the mindful student study): a pragmatic randomised controlled trial. The following questions refer to the above study by galante et al. The questions focus on critically appraising a randomized trial, which will be continued in next week"s tutorial. Our lecture in week 3 will further delve into selection bias, information bias, and confounding. Questions: describe what an experimental study is and the key characteristic that differentiates an experimental study from an observational study. Researchers introduce an intervention and study the effects. Several steps: formulare hypothesis, research proposal, recruitment based on eligibility, treatments according to a protocol. Researcher manipulation core difference: researcher in observational studies don"t have this.

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