ANA300Y1 Lecture Notes - Lecture 8: Hemolytic Disease Of The Newborn, Extracellular Fluid, Blood Type
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Document Summary
Metabolic wastes from peripheral tissue will go through blood and transported to kidney mostly for secretion. Involved in stabilization of interstitial fluid ph; composition of plasma and if in close contact, and their composition of electrolytes and ph are similar. Plasma (46-63%): h2o (92%, dissolved proteins (7%) Immunoglobulins (antibodies: recognize foreign pathogens/proteins and will bind to them; produced by white blood cells. Transport globulins: move lipid soluble substances around body; because they would diddolve in. Fibrinogen: constantly transported around in plasma; converted to insoluble form (fibrin) to induce clotting. Regulatory proteins: enzymes, proenzymes, hormones, plasma vs isf: Dissolved proteins are high in plasma, and low in isf. Which is why plasma can pull fluid back into blood stream from the isf; necessary for maintaining tissue fluid volume. Nutrients, wastes, aas are similar and transported. O2 higher in plasma: so it diffuses into isf; as oxygen is consumed, gradient is maintained. Electrolytes: freely in communication with interstitial fluid.