HMB200H1 Lecture Notes - Lecture 10: Substantia Nigra, Genetic Linkage, Cell Adhesion Molecule
Document Summary
Clinical focus 8. 2: asd: various links and videos posted. Origins of autism: environmental and genetic causes, autism genome project consortium, phenotypes of asd, r541c mouse model of asd. Only second half of readings will be tested, but the concepts are cumulative. You can"t really learn second half without first half. Asd is a lifelong neurodev disorder that affects how people communicate and relate to others. Range and intensity of disability varies, but all people affected have: Many have difficulty responding appropriately to their environment. The geneva centre for autism works to raise awareness for the disorder. Word autism coined by eugen bleuler, associated with schizophrenia, referring to the detachment of reality seen in this. It used to be a word for psychiatry / psychoanalysis and not biological neurology. Kanner, 1938: met 5yo donald who enjoyed isolation and was oblivious to his surroundings. Invented the category: early infantile autism, borrowing from bleuler.
