HMB204H1 Lecture Notes - Lecture 4: Gut Flora, Science Translational Medicine, Inflammatory Bowel Disease
28 Jan 2017
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Lecture 4 - evolution of the human gut microbiome. Understanding how antibiotics potentially alter the gut microbiome is critical to understanding our biology. Fairly new idea that alters the traditional concept of one microbe, one disease/pathology. Microbiota consist of all of the bacteria, viruses, and eukaryotes (i. e. fungi) that grow in and on the body (1014 bacteria internally; 1010 bacteria on skin; quadrillion viruses) Microbiota now thought to also play a role in health, not only disease. Microbiome all of the microorganisms and their collective genetic material that inhabit the human body or another environment. Specific microbe can lead to various disease. Microbiota (cid:314) all of the microbes that inhabit the human body. But the number of genes are 100 times more than human genome ! Microbes (importantly bacteria) are now thought to be able to suppress the growth of other bacteria/microbes that try to colonize their normal areas of growth.
