JHE353H1 Lecture Notes - Lecture 3: Central Dogma Of Molecular Biology

• School: UTSG
• Department: History and Philosophy of Science and Technology
• Course: JHE353H1
• Professor: Marga Vicedo

Document Summary

4 processes of evolution: adaptation, development, innovation and inheritance. Darwinism = will explain on an organismal level instead of a genetic level. The only pxc that darwin could explain was adaptation. Replicator biology: taking the four parts of evolution and saying what happens in terms of the gene. Inheritance = transmission of genes from parent to offspring. Development = rna/dna, innovation = mutation, adaptation = advantageous. Mendel said that we have to think about discrete pieces that are transmitters of inheritance. Inheritance transmission of genetic material from parent to offspring. Weiss(cid:373)a(cid:374)"s barrier: (cid:449)hat is at the (cid:272)e(cid:374)ter of this (cid:271)arrier. Mendel inheritance = transmission of particles = particles are building blocks of inheritance. Phe(cid:374)ot(cid:455)pes are(cid:374)"t refle(cid:272)ti(cid:448)e of ge(cid:374)ot(cid:455)pes, (cid:271)ut ge(cid:374)ot(cid:455)pes refle(cid:272)t phe(cid:374)ot(cid:455)pes. The phe(cid:374)ot(cid:455)pe (cid:272)a(cid:374)"t change the genotype if it gets selected. Cha(cid:374)ges (cid:271)rought to the so(cid:373)a duri(cid:374)g de(cid:448)elop(cid:373)e(cid:374)t (cid:272)a(cid:374)"t affe(cid:272)t the ger(cid:373) li(cid:374)e. this is a (cid:272)lear separatio(cid:374) between soma and germ cells.