IMM250H1 Lecture Notes - Lecture 9: Peripheral Tolerance, Sepsis, Multiple Sclerosis
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Lecture 9: overly active or (cid:373)isdirected i(cid:373)(cid:373)u(cid:374)e respo(cid:374)ses. Sepsis: sepsis is a severe form of systemic inflammation in response to infection, characterized by a whole-body inflammatory state (called a systemic inflammatory response syndrome or. Sirs) to the presence of a known or suspected infection. In response to high level of microbes or microbial products in blood: there is 4 forms of sepsis and sepsis-related conditions, sirs: systemic inflammatory response syndrome to a critical illness of infectious or non-infectious nature. Pathogenesis of septic shock: systematic infection cytokine release activation of the endothelial system (vasodilation, increased vascular permeability) loss of integrity of the circulatory system poor tissue perfusion and organ dysfunction. Bronchoconstriction: venous dilatation (blood doesn"t return to heart fatal hypotension) It was first thought that dietary avoidance of strong allergens during pregnancy and lactation will prevent allergy. Exclusively breastfeed for only the first 4-6 months of life and then introduce solid foods no avoidance of allergies after 4 months.
