NFS382H1 Lecture Notes - Lecture 6: Iodised Salt, Vitamin A Deficiency, Thyroid
22 Apr 2016
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Document Summary
70-80% is found in the thyroid found and fuction in the iodide (i-) form: rda is based on iodine overturn. Food of marine origin (vs fresh water) contain high levels of iodine. Dairy products contain iodine via additives added to animal feed and use of iodine-containing disinfectants on cows, milking machine and storage containers. Iodinzed salt in 1g has 100ug of iodine. Organic bound iodine is freed via digestion. Absorbed rapidly from stomach (and to a lesser extent the duodenum and completely) Made into thyroid hormones: thyroxin (t4, triiodothyronine (t3, effect of these hormones mediates via their occupancy on nuclear receptors with subsequent effect on gene expression. Transport of thyroid hormones in the blood: thyroxine-binding globulin, albumin, transthyretin (prealbumin, less thatn 0. 1% is not bound to a binding protein. Has an effect on lipolysis, enhances muscle contraction, bone growth and development, increase hr, stimulate nutrient digestion and absorption.
