PSL201Y1 Lecture Notes - Lecture 4: Axon Hillock, Threshold Potential, Afterhyperpolarization

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23 Apr 2015
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Gated channels voltage-gated (voltage change across membrane) ligand (chemically) gated (presence of a ligand) mechanically-gated (apply pressure) Response depends on which type of gated channel. Membrane potential changes depolarization with +ve change in membrane potential. Equilibrium potential for sodium is +60 mv equilibrium potential for ek is -90mv lastly you can see resting potential is -70 mv. Anytimes there is a difference in membrane potential membrane is polarized membrane potential is always referred to inside relative to outside. Reference point is -70 mv anything that brings that membrane potential above will call it depolarization anything that brings that membrane potential below the reference point will be called hyperpolarization. Repolarization occurs when membrane potential returns to resting stage. Types of electrical signals: graded potentials small communicate over short distances. Inhibitory: hyperpolarization graded potential can be depolarizing or hyperpolarizing, depolarizing= excitatory, hyperpolarizing=inhibitory.

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