PSL301H1 Lecture Notes - Lecture 22: Afferent Arterioles, Efferent Arteriole, Renal Blood Flow

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19 Mar 2017
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PSL301H1 Full Course Notes
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PSL301H1 Full Course Notes
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Glomerular anatomy: ultrafiltration and permselectivity, measurements: inulin, creatinine, albumin. Pre-lecture notes: electrolyte and water balance (kidney) lecture 2/8. 55 yo with long history of diabetes mellitus. Serum creatinine is 160 umol/l (normal 80 umol/l) Found to have 500 mg albumin in 24h urine collection. Ultrafiltration is affected with gfr dropping by half. Has a glomerular disease that affects permselectivity as well bc of albumin. Size is about 10cm, size of the fist. Most of the discussion takes place about functions in the cortex and medulla. Collecting system is the renal pelvis that brings urine down from ureter to the bladder. This is not by gravity - peristalsis is what drives it forward. Nephron - renal tubule goes into medulla and empties into the renal pelvis to bladder. This vasculature is very important - shows you the arteries that are going out to arborize. This focuses on the cortex and the capsule and shown below are the arterioles.

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