Biochemistry 2280A Lecture Notes - Lecture 11: Glycogen Phosphorylase, Glycogen Synthase, Pentose Phosphate Pathway

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Body is still doing these processes even when we are sleeping. 3 central compounds: glucose 6 phosphate, pyruvate, acetyl coa. Carbohydrate metabolism: glycogen synthesis and breakdown, glycolysis and fermentation, gluconeogenesis. Which meal will the friend request the day before her marathon: spaghetti and caesar salad, hamburger and onion rings, veggie soup, chili. Carbo-loading = day before race, long distance runners will load up in carbohydrate rich foods. Glycogen synthase enzyme that does this reaction. Needs to be driven forward needs a source of energy. Utp is going to be used not atp. Still has 3 phosphates just like atp and it can undergo similar hydrolysis which will have a similarly negative g value. Utp converted to udp get two phosphate: one from utp and one from glucose 1 phosphate, there is no phosphate in glycogen. Operates by different mechanisms than the first enzyme: accomplish the same thing but in reverse. Breaking glycogen or synthesizing glycogen: also has a g.

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