Biology 2382B Lecture Notes - Lecture 13: Axoneme, Dynein, Microtubule

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Cilia and flagella are two versions of the same thing but differ in length. Over 250 proteins: function of most of the proteins is unknown. Array of microtubule doublets that form a ring: a tubule 13 protofilaments, b tubule 10 protofilaments. The microtubules are held in place by proteins: nexin links the doublets together in a ring, radial spoke head proteins limit how much the doublets can move. Underneath each flagellum and cilium is a basal body, which is the. Mtoc: cilia and flagella arise from the basal body. Microtubules polymerize directly from the basal body. Basal bodies are often bound in pairs cilia and flagella often grow in pairs: ex chlamy is a good example. The two basal bodies are 90 degrees to each other: similar to centrioles. Cilia and flagella are also predominantly in animal cells just as centrioles are: maybe centrioles evolved from basal bodies. Remove a pair of doublets and looking in vitro.

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