Biology 2382B Lecture Notes - Lecture 14: Globular Protein, Microfilament, Polymerization
11 Mar 2020
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Microfilaments are important for cell shape and movement, including cell signaling. They have a cortical function act near the cell surface. There are several actin based structures, most near the cell surface. Actin can form networks: mts are linear and can form bundles, actin can form bundles, but it can also form branching networks, more complex than mts. Many isoforms of actin: alpha, beta and gamma actin, different isoforms form different structures but do basically the same thing (just in different locations) ignore that there are different isoforms. Globular protein, looks like a 4 leaf clover: g (globular) actin, monomer that is polymerized into f (filamentous) actin, microfilament that is the cytoskeletal component. F actin forms into a double helix: **do not need to memorize the structure/rotation. Actin polymerization is related to critical concentration. When you are adding actin monomers to a closed system there is polymerization above the.
