Biology 2382B Lecture Notes - Lecture 6: Spindle Apparatus, Dna Replication, Nuclear Membrane

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Coordination of growth with division ensuring faithful replication of. : gi - s - 62 (interphase) growth i mitotic phase growth. Prophase: nuclear envelope breaks down , spindle apparatus forms chromosomes condense chromatids metaphase plate separate towards spindle poles chromosomes flat are decordense , interphase , in nuclear membrane reassembles more rounded in mitosis. Replicates cell bud into lacks cycle stage inferred by. Long ga and m phases elongation occurs by formation of septum. Both defects yeast have temperature - sensation mutants ( cdc) proteins cell division in causing. Loss of cdc 2 achuty are heavily genes prevents cell from entering m conserved across eukaryotes cycle regulation. Mitosis promoting factor (mpf) : heterodimer of. M cdc 2 is always present , not always active. Cdks for different for occurs respective at checkpoints stage of transcriptional. Ubiquitin (ub) cell cycle level and by ubiquitin - mediated proteasome - dependent degradation. Ubiquitin addition of targeted for destruction ligases control.

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