Biology 2581B Lecture Notes - Lecture 6: Neurodegeneration, Dna Replication, Protein Folding
Document Summary
A t s can cause mutations out """ ( mutations. 739 repeats will result in hd (healthy) or may not have hd determines disease status and age of onset. Locus at protein folding neurodegeneration (normal development , top of chromosome 4 then degenerate) Dna is being copied is a potential site. An inappropriate detachment of the new strand from the template strand will cause a slippage of. Slip by one the new strand length , repeat recombination or repair forming a loop replication , Anticipation : t # of repeats and severity of t age of onset in future generations phenotype. Compensatory mutation : second mutation at for initial mutation"s lack of fitness growth on. T growth on low [antibiotic) higher cantibiotk] that location different compensates for. Reversion of mutation ( dna seq and phenotype) no net mutation. Suppressor : mutation at different location that restores phenotype 2 net mutations. A"- bt c- a- bt - a- b-