Biology 2581B Lecture Notes - Lecture 11: 1000 Genomes Project, Sequence Assembly, Ploidy
18 Mar 2020
School
Department
Course
Professor
Document Summary
Humans are the most represented in genetic research. Prior to hap , we knew : organisms before for the human genome common sequence at each ht humans chromosomes. Identify genetic differences and their frequencies between individuals and geographic populations. 501 frequency large families varies (far ) (close on. Some regions of the genome are more or. Re cut direct dna analysis sites in some regions but indicates gene distance chromosome) and decreases have a to less likely between closer markers record . event ( i 44 = 2003 with all goals accomplished ( ordered clone) Partial digestion : re cuts but not at every cut site resulting in overlap. Genetic and is key to sequence assembly physical maps provide the markers. Clones analyzed for markers / restriction sites config ( continuous dna seq) Subset of overlapping clones that cover chromosome are fractured and cloned.
